北京索萊寶科技有限公司
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服務熱線：18101056239
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
產品型號：K200018M
更新時間：2022-08-15
廠商性質：生產廠家
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| 英文名稱 | Anti-Bcl-2 Monoclonal Antibody |
|---|---|
| 宿主 | Mouse |
| 別名 | Apoptosis regulator Bcl 2;Bcl 2;B cell leukemia/lymphoma 2 |
| 應用 | WB IF |
| 稀釋比例 | WB 1:1000-2000. IF 1:100-200. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 26kDa |
| Gene ID | 596 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG1 |
| 免疫原 | A synthetic peptide coupled to KLH |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide coupled to KLH |
| Subcellular Locations | Mitochondrion outer membrane Nucleus membrane Endoplasmic reticulum membrane |
| Swiss Prot | P10415 |
| 克隆號 | 6B5 |
| 克隆類型 | Monoclonal Antibody |
| 背景資料 | BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.
Anti-Bcl -2 Monoclonal一抗 |
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